A multidisciplinary approach is warranted to provide antiviral treatment to patients suffering from depression.”
“Background: Diagnostic criteria for bronchiolitis are variable. Objective: To study how the risk factors for recurrent wheezing and asthma vary by different definitions of bronchiolitis.
Methods: Viral etiology and atopic characteristics were studied in 259 hospitalized wheezing children
(median age, 14 months; range, 0-36 months). The data were analyzed according to age (<6, <12, <24 and <36 months) and whether they had a history or no history of a previous wheezing episode. Sixteen viruses were detected by conventional AZD6738 chemical structure and molecular methods. Atopic characteristics included the presence of eczema, specific and total IgE responses, blood eosinophil count, and
modified asthma predictive index.
Results: Evidence of respiratory virus infection was found in 93% of the cases and allergic sensitization in 26% of the cases. Rhinovirus infections and atopic characteristics (sensitization, blood GSK1210151A research buy eosinophil count, and modified asthma predictive index) increased by age and were significantly more common in children with recurrent wheezing episodes than in first-time wheezers in age categories of <24 and <36 months (P < 0.05 for all).
Conclusions: In children with bronchiolitis, 2 clinical factors, age and number of previous wheezing episodes, are linked to inflammatory (atopy-related factors) and virologic risk factors of asthma (rhinovirus-associated disease). According to current US and UK guidelines,
bronchiolitis includes wheezing children <24 months of age. Our observations suggest that the clinical definition should include only children with their first episode of wheezing.”
“Tin (Sn) films of 1 mu m thick and 2-3 mu m grain size were electroplated over a silicon (Si) wafer. The wafer was first deposited with an adhesion layer of chromium (Cr) followed by a nickel (Ni) using the evaporation technique. A special fixture was used to apply a biaxial compressive stress to the Sn film. After exposing the sample to 160 degrees C under vacuum for seven days, large hillocks were observed having dimensions of 10-30 mu m in diameter and 30-150 mu m in length. The hillock density was approximately seven Tubastatin A mouse per square mm. A quantitative method was developed using surface mapping and MATLAB (TM) to estimate the volume of hillocks per unit area of the Sn film and thus, to relate that volume to the local compressive stress. The rate of growth was modeled as a flow of Sn atoms along the Sn/Ni interface under the applied pressure gradient. Reasonable viscosity and self-diffusivity were calculated, which suggested that Sn/Ni interface diffusion was potentially the mechanism for hillock growth. (C) 2010 American Institute of Physics. [doi:10.1063/1.3359658]“
“Background Inadequate access to oral health care places children at risk of caries.