Results: Of the 243 participants, 55 (22.6%) were hypertensive. Of these, 28 (50.9%) were males and 27 (49.1%) females. The probability of having HTN was significantly higher with increasing age with 7 (38.9%) of the participants >50 years of age. Similarly,
HTN increased proportionately with the participant’s body mass index. With regard to other risk factors, 13 (50%) of the diabetics, 10 (27.0%) of the dyslipidemic participants selleck chemicals and 9 (18.4%) of the cigarette-smoking participants had HTN. Conclusions: The occurrence of HTN was high and was strongly associated with diabetes, the aging process and obesity. Copyright (C) 2011 S. Karger AG, Basel”
“We sought to understand the experiences and perceptions of food producers
regarding food procurement programs for local institutions. A total of 72 (45%) Mississippi fruit and vegetable growers completed a mailed survey, and of those that reported selling to local businesses and institutions (54%), few were selling to schools (13%). The primary motivations to sell to institutions were to increase profits (67%) and to improve nutrition within their communities (57%), while the most commonly reported barrier was a lack of knowledge about how to sell to institutions (39%). Farm to institution programs must develop evidence-based practices designed to address barriers to producers’ participation in local institutional food procurement programs.”
“Rationale: Pericytes are key regulators of vascular maturation, LBH589 price but their value for cardiac repair remains
unknown.\n\nObjective: LY333531 in vitro We investigated the therapeutic activity and mechanistic targets of saphenous vein-derived pericyte progenitor cells (SVPs) in a mouse myocardial infarction (MI) model.\n\nMethods and Results: SVPs have a low immunogenic profile and are resistant to hypoxia/starvation (H/S). Transplantation of SVPs into the peri-infarct zone of immunodeficient CD1/Foxn-1(nu/nu) or immunocompetent CD1 mice attenuated left ventricular dilatation and improved ejection fraction compared to vehicle. Moreover, SVPs reduced myocardial scar, cardiomyocyte apoptosis and interstitial fibrosis, improved myocardial blood flow and neovascularization, and attenuated vascular permeability. SVPs secrete vascular endothelial growth factor A, angiopoietin-1, and chemokines and induce an endogenous angiocrine response by the host, through recruitment of vascular endothelial growth factor B expressing monocytes. The association of donor-and recipient-derived stimuli activates the proangiogenic and prosurvival Akt/eNOS/Bcl-2 signaling pathway. Moreover, microRNA-132 (miR-132) was constitutively expressed and secreted by SVPs and remarkably upregulated, together with its transcriptional activator cyclic AMP response element-binding protein, on stimulation by H/S or vascular endothelial growth factor B. We next investigated if SVP-secreted miR-132 acts as a paracrine activator of cardiac healing.