Authors’ contributions SS.. Data Collection, Data Interpretation. Manuscript Preparation, Literature Search. OK… Study Design, Manuscript Preparation, Data Interpretation. DA… Data Collection. Manuscript Preparation. AC… Data Collection, Literature Search. CA… Data Collection, Literature Search. MS… Study Design, Literature Search. All authors read and approved the final manuscript. Consent section Written informed consent was obtained from the patients’ relatives for publication of this case report. Mustafa Serinken, MD

Inhibitors,research,lifescience,medical Pre-publication history The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-227X/10/7/prepub Inhibitors,research,lifescience,medical Acknowledgements All contributors for this study are those included in the authors. Meanwhile, no source of funding from any third party was utilized in any phase of study design, writing and publication of the study.
Advanced Life Support (ALS) for the pre-clinical management of vitally compromised children consists

of endotracheal intubation and ventilation, intravenous or intra-osseous access with fluid replacement and administration of medication. The purpose of on-site advanced interventions is to stabilise the patient before transport to the hospital. These procedures are expected to reduce physiological Inhibitors,research,lifescience,medical deterioration, and thus to reduce mortality. However, this has never been proven on the basis of evidence. One of the confounding factors could be the (lack of) experience and the training required to perform the advanced interventions in a pre-clinical setting [1]. The Helicopter Emergency Medical Service (HEMS) was introduced in the Netherlands to provide optimal pre-clinical care for trauma patients by the Dutch government. Inhibitors,research,lifescience,medical The

HEMS, consists of a physician (anaesthesiologist or trauma surgeon), a flight nurse and a pilot/driver. When the HEMS became operational, the Emergency Medical Service (EMS) frequently asked for assistance in stabilizing vitally compromised children. There were no paediatric HEMS data available in the Netherlands, reEX 527 datasheet Search in other countries Inhibitors,research,lifescience,medical could not be easily extrapolated due to the international differences in HEMS and EMS organisations. However, MRIP there was a necessity to characterize the children involved to ameliorate HEMS and EMS care. The objective of this study was to evaluate the advanced medical interventions performed by the EMS and the HEMS in vitally compromised children, and to examine how often the HEMS provided additional medical care which was not or could not be provided by the EMS. Methods Prospective cohort analysis of all HEMS calls for all paediatric emergencies for which the HEMS in the eastern part of the Netherlands (HEMS Netherlands-East) was called out, in the years 2001 to 2009. Only children under the age of 16 on the day of the emergency call were included.