At the time of PB, the mean age of the patients was 64.7 years (range, 38–84 years). The tumor characteristics are summarized in Table 1. None of the

patients had palpable lymph nodes on initial physical examination. The treatment consisted in all cases of exclusive PB, low dose rate, with manual implantation of 192Ir. All uncircumcised patients had been circumcised before treatment. A Foley catheter was left in place until removal of the sources. The parameters of PB are summarized in Table 2. To evaluate not only the sexual function but also the sexual behavior of patients after treatment, we used the grid BASIC IDEA of Lazarus (6) and Cottraux et al. (7) that addresses nine areas, namely Behavior (B), Affect (A), Sensation (S), Imagery (I), Cognition (C), Interpersonal (I), Drugs GSK-3 beta pathway (D), Expectation PI3K inhibitor (E), and Attitude (A). A pretest was conducted among 5 patients who underwent surgery for phimosis after the age of 60 years. In common with the studied population, these patients were of the same age and had a similar history of disease of the terminal area of the penis (a history of inflammation). The final questionnaire includes 31 questions and takes about 20 min to be completed by the patient. The survey on sexuality also used the validated French version of the International Index of Erectile Function (IIEF) questionnaire that explores five domains (desire, erection, orgasm, satisfaction from sexual

relations, and overall satisfaction). In June 2010, we conducted a survey on sexuality among 21 French patients

in remission from their disease. After sending a newsletter, it was proposed to the patients that they complete the questionnaire on sexuality. Patients were considered as accepting to participate in the survey if they filled out the questionnaire. The study was approved by our Institutional Research Board. Finally, we obtained the participation of 19 of the 21 patients (90.5%). The participation of the patients is detailed in Fig. 1. The software used for the statistical data was Stata (Stata, Corp., College Station, TX). The χ2 test or Fisher exact test (F) were used for comparison of qualitative variables. The Mann–Whitney, Wilcoxon, or Kruskal–Wallis tests were used for the comparison of the distributions Interleukin-3 receptor of quantitative variables. The Spearman rank test was used to assess the correlation between quantitative variables. Survival tables were designed for each type of survival (overall, specific, and recurrence free), and were used to assess survival at different times of followup. Survival analysis was performed using the Kaplan–Meier method. Approximately 80 months after PB (12.8–189.8), 28 patients (59.6%) showed no recurrence, 16 (34%) experienced a local recurrence that required a partial (n = 15) or total amputation (n = 1), and 8 (17%) had regional and/or distant recurrence. The rate of preservation of the penis was 66% (n = 31). At the time of our survey, 23 (48.