There was also a highly significant interaction effect (F(1.581, 180.21) = 180.704,

P < 0.001). Examination of the means indicated that the change in mean mood self-ratings was much more pronounced for the sad mood group than for the happy mood group. Paired t-tests of successive mean mood scores for the sad mood group found that there was a significant decline in its Inhibitors,research,lifescience,medical mean mood ratings both between the first and second measurement times (t(57) = 7.953, P < 0.001) and between the second and third measurement times (t(57) = 5.02, P < 0.001). The predicted effects of mood induction on the two groups were fully confirmed. Figure 3 Differences between mood induction groups in self-ratings of mood before and after the two mood inductions. Mean scores for the sad and happy mood groups are shown for baseline mood rating (1), first postmood induction rating (2), and second postmood ... Internal Inhibitors,research,lifescience,medical consistency of stimuli In the second stage of the study, the focus was directed to determining whether the mood groups differed in their reactions to any of the valenced stimuli, and to whether the stimuli evoked different reaction times for the sample as a whole and differentially

for each mood group. The three reaction time measurements Inhibitors,research,lifescience,medical taken from the three Stroop trials obtained for each stimulus and for each subject were averaged into one score. These combined scores were considerably more reliable than single observation scores. All of the three-observation composite scores proved to be highly reliable Inhibitors,research,lifescience,medical (Cronbach’s α statistic ≥ 0.889) for the sample as a whole. Group differences on the verbal-emotional Stroop The difference between the two mood groups in their mean reaction times for each stimulus type in the verbal-emotional Stroop test was tested for significance by conducting a 2 (Group: sad, happy) × 4 (Verbal Valence: sad, fearful, neutral, happy) ANOVA. The results indicate a main effect of mood with sad mood being significantly

slower overall in their Inhibitors,research,lifescience,medical mean reaction time over the combined set of Pexidartinib ic50 valences on the verbal-emotional Stroop test, F(1, 114) = 4.76, P= 0.031, ηp2 = 0.040. Further inspection of the data revealed an interaction effect in mean reaction times between the two mood groups with the sad mood group having significantly longer latencies than the happy mood group for the sad words, F(1, 114) = 5.07, P= 0.005, ηp2 = 0.043). The other three verbal valences did not differ significantly between groups (all P values ≥ 0.05.) Farnesyltransferase Group differences on the color Stroop The difference between the two mood groups in their mean reaction times for the color Stroop test was tested for significance by conducting a one-way ANOVA with mood (sad and happy) as the independent variable and reaction time as the dependent variable. The results of this analysis indicate that there was no significant difference in mean reaction times between the two mood groups on the color Stroop test, F(1, 114) = 1.94, P= 0.166.