A perforation score helps stratify patients into different risk groups. Key Word(s): 1. esophagus; 2. perforation; 3. Boerhaave’s; 4. perforation score; Presenting Author: FAN FENG Additional Authors: HONGWEI ZHANG Corresponding Author: FAN FENG Affiliations: Xijing Hospital Objective: Dissection of subcarinal

lymph nodes is technically difficult in that it may cause main bronchus injury and prolong operation time. The aim of the present study was to evaluate the clinical outcomes of clinical T1N0 esophageal squamous cell carcinoma (ESCC) patients with or without subcarinal lymph nodes dissection. Methods: A total of 283 patients with ESCC had undergone three stage esophagectomy. The clinical and pathological features were collected and correlations NVP-LDE225 price with subcarinal lymph nodes metastasis were selleck products analyzed. The survival of patients was analyzed. Results: Tumor length, clinical

T, N and TNM stage, pathological T, N, and TNM stage were associated with subcarinal lymph node metastasis. The survival of T1N0 patients with subcarinal lymph nodes clearance was comparable to that without subcarinal lymph nodes clearance. No significant difference was found between the patients with subcarinal lymph nodes metastasis and patients without metastasis and had less than 4 subcarinal lymph nodes dissection (P > 0.05). The survival of patients without metastasis and had 4–6 subcarinal lymph nodes dissection was significantly higher than that of the patients Dipeptidyl peptidase without metastasis and had less than 4 nodes dissection (P < 0.05), while patients without metastasis and had more than 6 subcarinal lymph nodes dissection had no survival benefit compared to that of the patients had 4–6 nodes dissection (P > 0.05). Conclusion: For clinical T1N0 ESCC patients, subcarinal lymph nodes clearance may be unnecessary. For the rest ESCC patients, we recommend that at least 4 subcarinal lymph nodes should be removed in order to improve patients’ survival. Key Word(s): 1. Esophageal cancer; 2. Subcarinal lymphnode; Presenting Author: RAVINDRA SATARASINGHE Additional

Authors: SATHYAJITH AMBAWATTE, NAYOMISHERMILA JAYASINGHE, JAYEWARDENE RATHNAYAKE, RAVI WIJESINGHE, PUBUDU DE SILVA, NARTHANIRASENDRANRASENDRAN RASENDRAN Corresponding Author: RAVINDRA SATARASINGHE, NAYOMISHERMILA JAYASINGHE Affiliations: Sri Jayewardenepura General Hospital Objective: To study the prevalence and demographics of peptic ulcer disease in a cohort of adult Sri Lankans presented to a tertiary referral centre. Methods: Case notes of 2728 patients who had undergone upper gastrointestinal endoscopy for various reasons in the principle author’s unit at Sri Jayewardenepura General Hospital, Kotte, Sri Lanka from 15th of February 2002 to 15th February 2013 were retrospectively analyzed to obtain the required information. Results: There were178 patients having peptic ulcer disease with an age range of 24 to 92 years with a mean age of 62.3 ±13.5 SD years.