Blood 2007, 110: 735–742.CrossRef 10. Amy H, Monique LB, Renee XM, Meyling HC, Cheng C, Karin MK, Gritta EJ, Ulrich G, Ulrike BG, William EE, Rob P: The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia. Blood 2006, 107: 769–776.CrossRef 11. Matthew PC, Ainsley AC, Darren AC, Stacey LC, John WY, Nigel JP, Oliver LR, Gregory JM, Paul SC, Lynne RC, David M, Murray JB, David H, Robert WW, David GS, Kenneth JM, Alastair DR, Julie CH: Selective small molecule inhibitors of glycogen synthase kinase-3 selleck inhibitor modulate glycogen

metabolism and gene transcription. Chem Biol 2000, 7: 793–803.CrossRef 12. Peters SK, Douglas AM: A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci 1996, 93 (16) : 8455–8459.CrossRef 13. Tiffany H, Tracey AO, Robert K, Robert L, Sylvie this website S, Emma S, Geoff S, Alla D: Glycogen Synthase Kinase-3β Inhibition Preserves Hematopoietic Stem Cell buy 4SC-202 activity and Inhibits Leukemic Cell Growth. Stem Cell 2008, 26: 1288–1297.CrossRef 14. Ghosh JC, Altieri DC: Activation of p53-dependent apoptosis by

acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells. Clin Cancer Res 2005, 11: 4580–4588.PubMedCrossRef 15. Abbas S, Andrei O, Zhi WY, Bin Z, Mohammad HM, Daniel DB, Masayoshi M, Yutaka T, Toshinari M: Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation. Biochem Biophys Res Commun 2005, 334: 1365–1373.CrossRef 16. Mazor M, Kawano Y, Zhu H, Waxman J, Kypta RM: Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth. Oncogene 2004, 23: 7882–7892.PubMedCrossRef 17. Andrei VO, Martin EF, Vladimir NB, Thomas CS, Suresh TC, Daniel DB: Aberrant nuclear accumulation of glycogen synthase kinase-3β in human pancreatic cancer: association with kinase activity and tumor dedifferentiation. Clin Cancer Res 2006, 12: 5074–5081.CrossRef

18. Buss H, Dorrie A, Schmitz ML, Frank R, Livingstone M, Resch K, Kracht M: Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-κB activity. J Biol Chem Baf-A1 cell line 2004, 279: 49571–49574.PubMedCrossRef 19. Michael Karin : Nuclear factor-κB in cancer development and progression. Nature 2006, 441: 431–436.PubMedCrossRef 20. Véronique Baud, Michael Karin : Is NF-κB a good target for cancer therapy? Hopes and pitfalls. Nature 2009, 8: 33–40.CrossRef 21. Toni FD, Racaud-Sultan C, Chicanne G, Mas MV, Cariven C, Mesange F, Salles JP, Demur C, Allouche M, Payrastre B, Manenti S, Ysebaert L: A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia. Oncogene 2006, 25: 3113–3122.PubMedCrossRef 22. Aggarwal BB: Nuclear factor-kappaB: the enemy within.