PubMedCrossRef 8. Fothergill JL, White J, Foweraker JE, Walshaw MJ, Ledson MJ, Mahenthiralingam E, Winstanley C: Impact of Pseudomonas learn more aeruginosa genomic instability on the application of typing methods for chronic
cystic check details fibrosis infections. J Clin Microbiol 2010, 48:2053–2059.PubMedCrossRef 9. Mowat E, Paterson S, Fothergill JL, Wright EA, Ledson MJ, Walshaw MJ, Brockhurst MA, Winstanley C: Pseudomonas aeruginosa population diversity and turnover in cystic fibrosis chronic infections. Am J Respir Crit Care Med 2011, 183:1674–1679.PubMedCrossRef 10. Ciofu O, Mandsberg LF, Bjarnsholt T, Wassermann T, Hoiby N: Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants. Microbiology 2010, 156:1108–1119.PubMedCrossRef 11. D’Argenio DA, Wu M, Hoffman LR, Kulasekara HD, Deziel E, Smith EE, Nguyen H, Ernst RK, Larson Freeman Stem Cells inhibitor TJ, Spencer DH, Brittnacher M, Hayden HS, Selgrade S, Klausen M, Goodlett DR, Burns JL, Ramsey BW, Miller SI: Growth phenotypes of
Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients. Mol Microbiol 2007, 64:512–533.PubMedCrossRef 12. Feliziani S, Lujan AM, Moyano AJ, Sola C, Bocco JL, Montanaro P, Canigia LF, Argaraña CE, Smania AM: Mucoidy, quorum sensing, mismatch repair and antibiotic resistance in Pseudomonas aeruginosa from cystic fibrosis chronic airways infections. PLoS One 2010, 5:e12669.13.CrossRef 13. Govan JR, Deretic V: Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Adenosine Burkholderia cepacia . Microbiol Rev 1996, 60:539–574.PubMed 14. Hancock RE, Mutharia LM, Chan L, Darveau RP, Speert DP, Pier GB: Pseudomonas aeruginosa isolates from patients with cystic fibrosis: a class of serum-sensitive, nontypable strains deficient in lipopolysaccharide O side chains. Infect Immun 1983, 42:170–177.PubMed
15. Mahenthiralingam E, Campbell ME, Speert DP: Nonmotility and phagocytic resistance of Pseudomonas aeruginosa isolates from chronically colonized patients with cystic fibrosis. Infect Immun 1994, 62:596–605.PubMed 16. Smith EE, Buckley DG, Wu Z, Saenphimmachak C, Hoffman LR, D’Argenio DA, Miller SI, Ramsey BW, Speert DP, Moskowitz SM, Burns JL, Kaul R, Olson MV: Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc Natl Acad Sci USA 2006, 103:8487–8492.PubMedCrossRef 17. Yang L, Jelsbak L, Molin S: Microbial ecology and adaptation in cystic fibrosis airways. Environ Microbiol 2011, 13:1682–1689.PubMedCrossRef 18. Brown RK, Kelly FJ: Evidence for increased oxidative damage in patients with cystic fibrosis. Pediatr Res 1994, 36:487–493.PubMedCrossRef 19. Williams BJ, Dehnbostel J, Blackwell TS: Pseudomonas aeruginosa : host defence in lung diseases. Respirology 2010, 15:1037–1056.PubMedCrossRef 20.